Coagulation Sciences is developing technology that will scientifically support blood transfusion decisions. Such technology is sorely needed, as at least 40% of all administered blood transfusions are unnecessary. The first intended use is during cardiac surgery. Additional intended uses are planned to follow, including other surgeries associated with major bleeding.

Operating Rooms

Large amounts of bleeding, due to abnormalities in the blood, can significantly prolong the length of surgery. The more time required to arrest bleeding, the greater the cost, as operating rooms cost approximately $40 – $60 per minute. However, many insurance companies reimburse based upon procedure codes, not the length of surgery. Therefore, less time in the operating room translates into higher revenue for the hospital.

Emergency Rooms

Traumatic coagulopathy is often present by the time accident victims reach the Emergency Room. Coagulation Sciences’ Multiple Coagulation Test System will compare the ability of multiple therapies to stop bleeding in approximately 10 minutes. This information will supplement that provided by existing tests and will aid physicians in selecting blood products and pharmaceutical products required to restore clotting to normal. This is especially important in trauma victims, as delay in treatment of traumatic coagulopathy results in higher mortality.

Medical Laboratory

The MCTS will determine the optimal treatment and dose of therapy for patients with a multitude of bleeding disorders. Use of the MCTS will result in therapy that is individualized for each patient. This will be especially useful in hospitals that do not perform coagulation factor levels on a STAT basis.


Patients know that blood transfusions are associated with risks. Still, transfusions may be life-saving. Therefore, these risks often must be accepted. However, what is not commonly known is that at least 40% of administered blood transfusions are unnecessary. Coagulation Sciences MCTS will be the first fully automated Transfusion Management System. Though not all transfusions can be avoided, the use of the MCTS will ensure those transfusions that are administered are truly necessary.

 Scientific Research

The Multiple Coagulation Test System may be used for research purposes to assess potency of anti-coagulants, and dose-response curves, in-vitro.